About 26 people are suspected to have died of Lassa fever in seven states across Nigeria.
More than 150 others are feared to have been infected, the head of Nigeria's Centre for Disease Control Abdussalam Nasidi said.
Health officials were still carrying out tests to confirm the numbers.
"It could be lower but we need to wait for different laboratory tests before arriving at a definite figure," Mr Nasidi added.
Cases had been reported from states in the north and south - including the most populous, Kano, and the oil-rich Rivers State, he said.
Lassa fever is is transmitted to humans from rodents that harbour the virus. The most common complication of the virus is deafness.
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